In Situ Hybridization (ISH)

In situ hybridization (ISH) kits are tools for the detection of specific nucleic acid sequences, which help identify molecular features of diseases and aid in pathological diagnosis by providing accurate gene and chromosome localization information. Based on a diversified portfolio of IVD products and cutting-edge diagnostic technologies, Alta DiagnoTech offers several types of ISH kits, such as CISH, FISH, SISH, and RNA ISH kits, to meet the challenges of complexity and precision in clinical diagnostics.

Overview of ISH

ISH is a commonly used laboratory technique for analyzing gene expression and the localization of specific DNA and RNA molecules in cells and is an important tool for basic science research and clinical diagnosis. According to the type of method for in situ RNA and DNA target display, it can be divided into fluorescence in situ hybridization (FISH), chromogenic in situ hybridization (CISH) and silver-enhanced in situ hybridization (SISH).

Fig.1 Detection of RNA in breast cancer cells using ISH. (Veselinyová, et al., 2021)

Applications of ISH Products in IVD

With the advancement of technology, ISH products have been continuously developed and optimized, and they play an important role in the field of IVD, such as cancer diagnosis, genetic disease screening, and infectious disease detection, providing important support for precision medicine and personalized treatment.

We offer custom products for a variety of application scenarios to support a wide range of important areas such as pathogen identification, mutation monitoring, and individualized medical evaluation.

• FISH Test Kits
  Our FISH kits provide accurate and efficient detection of chromosomal abnormalities, aiding scientists and clinicians in complex genetic analysis.

• CISH Test Kits
  Using our CISH kits, clients to detect and identify gene expression in tissue sections in a stable manner, providing reliable data support for pathology diagnosis.

• SISH Test Kits
  Our carefully selected SISH kits provide users with a solution for obtaining clear gene expression results without the need for fluorescence microscopy, enhancing the convenience and practicality of the experiment.

• RNA ISH Test Kits
  Our RNA ISH kits have helped researchers pinpoint and quantify RNA molecules in cells, driving advances in gene expression research.

• Multiple ISH Test Kits
  We offer multiple ISH kits that permit users to analyze multiple target molecules simultaneously, thereby obtaining more comprehensive biological information in a single experiment.

• Quantitative ISH Test Kits
  With our quantitative ISH kits, users achieve accurate determination of the expression of target molecules to support in-depth molecular biology studies.

Alta DiagnoTech offers a line of ISH kits that provide efficient and accurate assays for modern scientific research and IVD. Regardless of your research direction, we offer a tailor-made product portfolio to help you succeed in diverse applications. Please feel free to contact us, we are happy to provide you with more information and support.