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| Product Name | Magrose COOH (30-150 µm) |
| Catalog No. | SM-HMM-0022 |
| Description | Agarose-coated magnetic beads can be used for enrichment, separation and purification of biomolecule (proteins, peptides, oligonucleotides, drug molecules, etc.). They have abundant active functional groups, faster magnetic responsiveness, and lower non-specific adsorption. |
| Features | Rich in carboxyl groups: ~1000 µmol/g; Good operation performance: the magnetic beads are uniformly dispersed and superparamagnetic, magnetic response time ＜10s; Good stability and batch-to-batch reproducibility, CV of carboxyl group content between batches <5%; High binding amount of target substances, low non-specific adsorption: dedicated to the field of separation and purification. |
| Average Particle Size | 30-150 µm |
| Surface Group / Content | COOH (~120 µmol/g) |
| Magnetic Core | Fe3O4 |
| Shell | Agarose |
| Magnetism Type | Superparamagnetic |
| Saturation Magnetization Strength | 30~50 emu/g |
| Concentration | 20% (v/v) |
| Applications | Protein Purification Immunoassay Drug Screening and Delivery |
Magnetic beads have become indispensable tools in modern biological research and biotechnology, revolutionizing the processes of biomolecule separation, purification, and analysis. Among various types of magnetic beads, agarose-coated magnetic beads stand out for their biocompatibility and ability to functionalize with active groups, making them ideal for targeting specific biomolecules.
Magrose COOH (30-150 µm) is developed based on the growing demand for efficient, reliable, and scalable biomolecule manipulation in research settings. The integration of Fe₃O₄ magnetic cores with agarose shells combines the strong magnetic responsiveness of Fe₃O₄ with the low non-specific adsorption and excellent biocompatibility of agarose, addressing key pain points in traditional purification methods such as low yield, high impurity levels, and complex operation steps.
This product is designed specifically for research applications, catering to the needs of laboratories engaged in protein science, immunology, molecular biology, and drug discovery. It provides a robust platform for enriching and purifying proteins, peptides, oligonucleotides, and drug molecules, supporting a wide range of experimental workflows from sample preparation to downstream analysis.
Abundant carboxyl groups with a surface content of ~120 µmol/g, enabling efficient conjugation with biomolecules through amide bond formation or other coupling reactions.
Superparamagnetic property ensures rapid magnetic response (＜10s) for fast separation, while avoiding magnetic particle aggregation after the removal of external magnetic fields.
Uniform particle size distribution (30-150 µm) promotes consistent performance across experiments, ensuring reproducible results in batch-to-batch use.
High saturation magnetization strength (30~50 emu/g) facilitates quick and complete separation under magnetic field, reducing processing time and improving workflow efficiency.
20% (v/v) concentration offers optimal handling and dispersion, balancing viscosity and reactivity for easy operation in various experimental setups.
Excellent stability and batch-to-batch reproducibility, with a coefficient of variation (CV) of carboxyl group content below 5%, ensuring reliable performance in long-term research projects.
Low non-specific adsorption due to the inert agarose shell, minimizing interference from unwanted biomolecules and enhancing the purity of target analytes.
Superior biocompatibility of agarose shells reduces damage to biomolecules, preserving their structural and functional integrity during purification and separation processes.
Faster magnetic responsiveness (＜10s) compared to many conventional magnetic beads shortens experimental time, improving workflow efficiency and throughput.
High binding capacity for target substances, driven by abundant carboxyl groups, allows for efficient enrichment even from low-concentration samples, maximizing recovery yield.
Minimal non-specific adsorption ensures high-purity outputs, reducing the need for additional purification steps and saving time and resources in downstream applications.
Consistent batch-to-batch performance (CV ＜5% for carboxyl content) eliminates variability risks, providing reliable and comparable results across different experiments and research phases.
Versatile applicability across multiple research areas, including protein purification, immunoassays, and drug screening, offering a multi-functional solution for diverse laboratory needs.
Easy to use and integrate into existing experimental protocols, requiring no specialized equipment beyond a magnetic separator, lowering the barrier to adoption for research teams.
For research use only, not for clinical use.
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